AAV CAG-fLuc

AAV CAG-fLuc

Cat. #: M1483
Availability: In Stock
$589.00
-+
Product Category:   Knockdown Validated Polyclonal Antibody
Synonyms:   Nuclear Receptor Subfamily 3 Group C Member 1;Glucocorticoid Receptor; Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) ; GRL; GR; Nuclear Receptor Subfamily 3 Group C Member 1 Variant HGR-B(54) ;Nuclear Receptor Subfamily 3 Group C Member 1 Variant HGR-B(77) ; Nuclear Receptor Subfamily 3 Group C Member 1 Variant HGR-B(93) ; Nuclear Receptor Subfamily 3, Group C, Member 1; Glucocorticoid Nuclear Receptor Variant 1; GCRST;GCCR; GCR
UniProt Entry:   P04150 
NCBI Gene Entry:   2908 
Molecular Weight:   91,94 kDa 
Clonality:   Rabbit polyclonal antibody
Species Reactivity:   Human
Applications:   WB/IC/F 
Recommended Dilution:   WB 1:1000 / IC 1:100 / F 1:100
Immunogen:   Recombinant fragment of human NR3C1
Isotype:   Rabbit IgG 
Storage Buffer:   Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide  
Storage:   At –20°C
Background:   NR3C1 gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance.
Documents: Please contact us to request the manual

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